Connaught, nonetheless, had provide you with a artificial, liquid progress combination, generally known as Medium 199, for most cancers cell analysis that produced extra virus, extra shortly and with out contamination. It was supplied to Dr. Salk for his polio efforts.
It was Dr. Farrell, certainly one of a very small variety of girls then working as analysis chemists in Canada, who discovered the way to safely produce huge portions of virus in Medium 199. Adapting earlier work, she developed what got here to be generally known as the Toronto Method. Racks of specifically designed machines gently rocked bottles of Method 199 and the virus.
Her subsequent process was to get sufficient machines constructed and to rent sufficient certified workers to make not solely sufficient virus for the checks in the United States, Canada and Finland, but in addition to create sufficient vaccine to inoculate all of Canada’s kids. In a bid to speed up vaccination, the Canadian authorities gambled and positioned an order with Connaught earlier than realizing if the Salk vaccine would show secure and efficient in checks.
It did, with the end result made public on April 12, 1955, the day earlier than Dr. Farrell’s birthday. “I could not help feeling that I had received a pretty fine present,” she mentioned in a speech that fall.
Variations of the Toronto Method had been used till the 1970s to make polio vaccines, Dr. Rutty advised me. Apparently, at Dr. Farrell’s request, Connaught determined to not patent the method.
Dr. Rutty, who’s the professional relating to Canada’s position in polio analysis and who serves because the historian for Connaught’s successor firm, Sanofi Pasteur Canada, mentioned that frustratingly little is understood about Dr. Farrell’s private life. She by no means married, as was the case with many different girls in Canadian medical analysis, nor had kids.